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With typical freebase vape juice, he says, “When you activate your e-cigarette and you’re inhaling that aerosol, what you find in your mouth is that the freebase evaporates off the aerosol droplets.” That means, according to O’Connell, that freebase e-liquid delivers less nicotine to the lungs and more nicotine to the upper respiratory tract where it’s absorbed into the body at a slower rate